Rosette nanotubes Rosette nanotubes are tubes of nanometric sizes obtained through the self-assembly of organic molecular components.
The basic unit for the self-assembly of rosette nanotubes is a base borrowing the structural properties of guanine and cytosine. Thus, the basic unit is hydrophobic and has complementary donor-donor-acceptor and acceptor-acceptor-donor H-bond arrays on its sides.
The self-assembly process takes place in two stages. At first, six basic units self-assemble into a supermacrocycle ring. In the second stage, supermacrocycle rings stack forming a nanotube with a central hollow pore.
Although very recently discovered (2001) rosette nanotubes allow us to envision interesting applications due to their tubular structure combined with the flexibility given by organic chemistry, which opens up a large range of possibilities for their functionalization.
It is thought that rosette nanotubes could one day be used for othopaedic implants since one can attach growth factors and specific bone recognition peptide sequences that will preferentially attract bone cell adhesion.
Similarly to the peptide nanotubes, rosette nanotubes could act as antibiotics by inserting in to the membrane of bacteria and sucking up nutrients.
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This multimedia resource is a sample excerpt from the Exploring Nanotechnology
CD-ROM, 3rd tome of the NANOPOLIS encyclopedia series. The CD-ROM is available for purchase.